It is approved for the treatment of mania associated with bipolar disorder (also known as manic depression), seizures (epilepsy), and migraine headaches
Feb 1, 2024 · Descriptions Divalproex sodium is used to treat certain types of seizures (epilepsy)
May 5, 2015 · Valproic acid (VPA) is one of the most prescribed drugs in children with newly diagnosed epilepsy
Nov 11, 2022 · Continuing Education Activity Drug-induced hepatotoxicity is an acute or chronic liver injury secondary to drugs or herbal compounds
While the liver can often repair itself after a period of alcohol use, the chronic, heavy consumption of alcohol can
have or think you have a genetic liver problem caused by a mitochondrial disorder such as Alpers-Huttenlocher syndrome
Liver failure
If there are symptoms of liver disease, they may include: Yellowing of the skin and the whites of the eyes, called jaundice
You should not use divalproex if you have liver disease, a urea cycle disorder, low platelet counts, or a genetic disorder such as Alpers' disease or Alpers-Huttenlocher syndrome
These risks are expected to go away if you stop taking Depakote
Long-term VPA therapy is also related to increased risk for the development of non-alcoholic fatty liver disease (NAFLD)
Call your healthcare provider between visits as needed, especially if you are worried about symptoms
Depakote should not be taken by people with compromised liver function
The risk of getting this serious liver damage is more likely to happen within the first 6 months of treatment
If you are using Depakote to treat epilepsy or manic episodes Valproic acid (VPA) is one of the most prescribed drugs in children with newly diagnosed epilepsy
change in personality
The risk of getting this serious liver damage is more likely to happen within the first 6 months of treatment
In some people, hyperammonemia may be clinically significant, resulting in hyperammonemic encephalopathy, which may be severe